Welcome to LookChem.com Sign In|Join Free
  • or
[1,2,4]Triazolo[1,5-a]pyrimidin-5(1H)-one is a heterocyclic chemical compound with the molecular formula C5H4N4O. It belongs to the class of triazolopyrimidines and has been recognized for its diverse pharmacological activities, including potential applications as an anti-cancer, anti-inflammatory, and anti-microbial agent. [1,2,4]Triazolo[1,5-a]pyrimidin-5(1H)-one has also been studied for its effects on the central nervous system, its ability to inhibit specific enzymes, and its potential use in treating neurodegenerative diseases. Its unique structure and wide-ranging activities make it a promising candidate for further research and development in medicinal chemistry.

14384-66-8

Post Buying Request

14384-66-8 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

14384-66-8 Usage

Uses

Used in Pharmaceutical Industry:
[1,2,4]Triazolo[1,5-a]pyrimidin-5(1H)-one is used as a potential therapeutic agent for various medical conditions due to its diverse pharmacological properties. It is being investigated for its anti-cancer activity, where it may help in the treatment of different types of cancer by targeting and inhibiting the growth of cancer cells.
Used in Anti-Inflammatory Applications:
In the field of anti-inflammatory drugs, [1,2,4]Triazolo[1,5-a]pyrimidin-5(1H)-one is used as a potential agent to alleviate inflammation. Its anti-inflammatory properties may help in reducing swelling, pain, and other symptoms associated with inflammation.
Used in Anti-Microbial Applications:
[1,2,4]Triazolo[1,5-a]pyrimidin-5(1H)-one is also used as a potential anti-microbial agent, showing promise in the treatment of bacterial and fungal infections. Its ability to inhibit the growth of microorganisms makes it a candidate for further development as an antimicrobial drug.
Used in Central Nervous System Applications:
[1,2,4]Triazolo[1,5-a]pyrimidin-5(1H)-one is used as a potential central nervous system stimulant, which may help in enhancing cognitive functions and treating conditions related to cognitive decline or neurological disorders.
Used in Enzyme Inhibition:
[1,2,4]Triazolo[1,5-a]pyrimidin-5(1H)-one is also being explored for its potential as an enzyme inhibitor, which could have applications in various therapeutic areas, including the treatment of specific diseases that involve enzyme dysregulation.
Used in Neurodegenerative Disease Treatment:
[1,2,4]Triazolo[1,5-a]pyrimidin-5(1H)-one is used as a potential therapeutic agent in the treatment of neurodegenerative diseases, such as Alzheimer's, Parkinson's, and other conditions characterized by the progressive loss of nerve cells in the brain. Its potential neuroprotective properties make it a promising candidate for further research in this area.

Check Digit Verification of cas no

The CAS Registry Mumber 14384-66-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,3,8 and 4 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 14384-66:
(7*1)+(6*4)+(5*3)+(4*8)+(3*4)+(2*6)+(1*6)=108
108 % 10 = 8
So 14384-66-8 is a valid CAS Registry Number.

14384-66-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one

1.2 Other means of identification

Product number -
Other names 5-Oxo-4,5-dihydro-s-triazolo <1,5-a> pyrimidin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:14384-66-8 SDS

14384-66-8Downstream Products

14384-66-8Relevant academic research and scientific papers

5-oxo and 7-oxo derivatives of [1,2,4]triazolo-[1,5-a]pyrimidine: Characterization and theoretical study

Abul Haj,Salas,Quirós,Molina,Faure

, p. 165 - 172 (2000)

4,5-Dihydro-5-oxo-[1,2,4]triazolo-[1,5-a]pyrimidine (5HtpO) and 4,7- dihydro-7-oxo-[1,2,4]triazolo-[1,5-a]pyrimidine (7HtpO) have been synthesized by the condensation of 3-amino-[1,2,4]triazole with a reagent bearing the three carbon atoms that close the six-membered ring in a strongly acidic (7HtpO) or strongly basic (5HtpO) medium. The crystal structures of these compounds have been determined by X-ray diffraction, exhibiting the N4-H tautomer, as expected from the RHF/AMI calculations. The different possibilities for binding metal ions are discussed from the MO results. (C) 2000 Elsevier Science B.V.

Synthetic Versatility of β-Alkoxyvinyl Trichloromethyl Ketones for Obtaining [1,2,4]Triazolo[1,5- a ]pyrimidines

Souza, Laura A.,Santos, Josiane M.,Mittersteiner, Mateus,Andrade, Valquiria P.,Lobo, Marcio M.,Santos, Felipe B.,Bortoluzzi, Adailton J.,Bonacorso, Helio G.,Martins, Marcos A. P.,Zanatta, Nilo

, p. 3686 - 3695 (2018)

The synthetic versatility of 4-alkoxy-4-alkyl/aryl-1,1,1-trichloroalk-3-en-2-ones (enones) for the synthesis of [1,2,4]triazolo[1,5- a ]pyrimidines, in which the trichloromethyl group is either maintained or eliminated from the product by simply controlli

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 14384-66-8