14384-67-9

Upstream product

• 5346-38-3 pyridine-2-carbothioamide 
• 532-27-4 1-chloroacetophenone 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 14485-04-2 3-phenyl-5,6-dihydro-pyrido[1,2-a]thiazolo[2,3-c]pyraziniumylium; bromide 
• 14384-72-6 1-(2-oxo-2-phenyl-ethyl)-2-(4-phenyl-thiazol-2-yl)-pyridinium; bromide 
• 14384-73-7 1-(2-oxo-propyl)-2-(4-phenyl-thiazol-2-yl)-pyridinium; bromide 

Relevant academic research and scientific papers

Fluorescent Sensing of both Fe(III) and pH Based on 4-Phenyl-2-(2-Pyridyl)Thiazole and Construction of OR Logic Function

In the presented paper we investigated a 2-pyridylthiazole derivative, 4-phenyl-2-(2-pyridyl)thiazole (2-PTP), as the molecular fluorescent switches. It was firstly found that 2-PTP could perform a “turn-on” fluorescent sensing for Fe(III) with selectivity and reversibility. A 2:1 stoichiometry between 2-PTP and Fe(III) was determined according to the molar ratio method. The binding constant was evaluated as (1.90?±?0.05)?×?105 (L/mol)2. The detection limit was found as 2.2?×?10?7?M (S/N?=?3). Secondly, 2-PTP also exhibited a pH-dependent dual-emission. The pKa(2-PTP-H+/2-PTP) value was then estimated as 2.0. To explain the identical emission at 479?nm of both the Fe(III) coordinated form and the protonated form of the ligand, we proposed a “locked” conformation. Finally, combining the two external stimuli as inputs, an OR logic gate was constructed using the fluorescent emission at 479?nm as the output channel.