14384-67-9

Basic information

• Product Name: 4-Phenyl-2-(2-pyridyl)thiazole, 97%
• Synonyms: 4-Phenyl-2-(2-pyridyl)thiazole, 97%;4-phenyl-2-pyridin-2-yl-1,3-thiazole
• CAS NO: 14384-67-9
• Molecular Formula: C₁₄H₁₀N₂S
• Molecular Weight: 238.3076
• Mol File: 14384-67-9.mol

Chemical Properties

• Melting Point: 55-59℃
• Appearance: /
• CAS DataBase Reference: 4-Phenyl-2-(2-pyridyl)thiazole, 97%(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Phenyl-2-(2-pyridyl)thiazole, 97%(14384-67-9)
• EPA Substance Registry System: 4-Phenyl-2-(2-pyridyl)thiazole, 97%(14384-67-9)

Safety Data

• Hazardous Substances Data: 14384-67-9(Hazardous Substances Data)

Upstream product

• 5346-38-3 pyridine-2-carbothioamide 
• 532-27-4 1-chloroacetophenone 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 14485-04-2 3-phenyl-5,6-dihydro-pyrido[1,2-a]thiazolo[2,3-c]pyraziniumylium; bromide 
• 14384-72-6 1-(2-oxo-2-phenyl-ethyl)-2-(4-phenyl-thiazol-2-yl)-pyridinium; bromide 
• 14384-73-7 1-(2-oxo-propyl)-2-(4-phenyl-thiazol-2-yl)-pyridinium; bromide 

Relevant articles and documents

Fluorescent Sensing of both Fe(III) and pH Based on 4-Phenyl-2-(2-Pyridyl)Thiazole and Construction of OR Logic Function

In the presented paper we investigated a 2-pyridylthiazole derivative, 4-phenyl-2-(2-pyridyl)thiazole (2-PTP), as the molecular fluorescent switches. It was firstly found that 2-PTP could perform a “turn-on” fluorescent sensing for Fe(III) with selectivity and reversibility. A 2:1 stoichiometry between 2-PTP and Fe(III) was determined according to the molar ratio method. The binding constant was evaluated as (1.90?±?0.05)?×?105 (L/mol)2. The detection limit was found as 2.2?×?10?7?M (S/N?=?3). Secondly, 2-PTP also exhibited a pH-dependent dual-emission. The pKa(2-PTP-H+/2-PTP) value was then estimated as 2.0. To explain the identical emission at 479?nm of both the Fe(III) coordinated form and the protonated form of the ligand, we proposed a “locked” conformation. Finally, combining the two external stimuli as inputs, an OR logic gate was constructed using the fluorescent emission at 479?nm as the output channel.