143840-10-2

Upstream product

• 117213-96-4 3-((E)-3-Phenyl-allyl)-pentanedioic acid diethyl ester 
• 796104-41-1 ethyl (2E,5E)-6-phenyl-2,5-hexadienoate 

Downstream Products

• 147438-59-3 (3R,5R,6R)-3-(2-Benzyloxy-ethyl)-7-(tert-butyl-diphenyl-silanyloxy)-6-methyl-heptane-1,5-diol 
• 143812-50-4 (Z)-(S)-5-(2-Benzyloxy-ethyl)-2-methyl-hepta-2,6-dienoic acid ethyl ester 
• 147438-54-8 (4R,6R)-6-((S)-2-Benzenesulfonyl-1-methyl-ethyl)-4-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-tetrahydro-pyran-2-one 
• 147438-58-2 [(Z)-(S)-5-(2-Benzyloxy-ethyl)-2-methyl-hepta-2,6-dienyloxy]-tert-butyl-diphenyl-silane 
• 143812-48-0 C₂₇H₃₀OSe 
• 143812-49-1 (R)-3-(2-Benzyloxy-ethyl)-pent-4-enal 
• 143812-44-6 (R)-4-((E)-3-Phenyl-allyl)-tetrahydro-pyran-2-one 

Relevant academic research and scientific papers

The first total synthesis of the antitumor macrolide rhizoxin: Synthesis of the key building blocks

The construction in optically pure form of the key building blocks, arising from our retro synthetic analysis of the antitumor macrolide rhizoxin is described.

Synthetic study on an antitumor antibiotic rhizoxin using an enzymatic process on prochiral β-substituted glutarates

Enantio- and stereoselective synthesis of the right-half segment (1; C1-C9) of the macrolide antibiotic rhizoxin has been achieved by enzymatic approach.Characteristic features of the present synthesis are (i) enantioselective hydrol

Enantioselective Hydrolysis of Dialkyl 3-Monosubstituted Glutarates with Pig Liver Esterase: Structure-Optical Purity Relationships

Dialkyl 3-monosubstituted glutarates are subjected to hydrolysis with pig liver esterase to afford the corresponding chiral half-esters.Synnthetically useful half-esters of higher optical purity are obtained from the prochiral substrates of more hydrophob