1438404-68-2Relevant academic research and scientific papers
Synthesis of stereochemically and skeletally diverse fused ring systems from functionalized C-glycosides
Gerard, Baudouin,Lee, Maurice D.,Dandapani, Sivaraman,Duvall, Jeremy R.,Fitzgerald, Mark E.,Kesavan, Sarathy,Lowe, Jason T.,Marié, Jean-Charles,Pandya, Bhaumik A.,Suh, Byung-Chul,O'Shea, Morgan Welzel,Dombrowski, Michael,Hamann, Diane,Lemercier, Berenice,Murillo, Tiffanie,Akella, Lakshmi B.,Foley, Michael A.,Marcaurelle, Lisa A.
, p. 5160 - 5171 (2013/07/26)
A diversity-oriented synthesis (DOS) strategy was developed for the synthesis of stereochemically diverse fused-ring systems containing a pyran moiety. Each scaffold contains an amine and methyl ester for further diversification via amine capping and amide coupling. Scaffold diversity was evaluated in comparison to previously prepared scaffolds by a shape-based principal moments of inertia (PMI) analysis.
