14385-64-9Relevant articles and documents
Synthesis, characterization, DFT, docking studies and molecular dynamics of some 3-phenyl-5-furan isoxazole derivatives as anti-inflammatory and anti-ulcer agents
M, Pallavi H,Al-Ostoot, Fares Hezam,Vivek, Hamse Kameshwar,Khanum, Shaukath Ara
, (2021/11/17)
A vast number of nitrogen heterocyclic derivatives comprising oxygen atom is considered as a valuable combination of therapeutic agents in curative chemistry. In particular, isoxazole, a five-member heterocyclic ring, is detected along with some of the ma
Synthesis and anti-proliferative assessment of triazolo-thiadiazepine and triazolo-thiadiazine scaffolds
Boraei, Ahmed T.A.,Ghabbour, Hazem A.,Gomaa, Mohamed S.,El Ashry, El Sayed H.,Barakat, Assem
, (2019/12/27)
A series of triazolo-thiadiazepines 4a-k were synthesized with excellent yields using dehydrated PTSA as a catalyst in toluene. Two triazolo-thiadiazines were obtained; 8a was formed directly by reflux in ethanol, whereas, PTSA promoted the formation of 8
Furanyl Cyclic Ethers: Single and Double Diastereoselectivity in the Synthesis of 2,4-Di and 2,4,5-Trisubstituted Tetrahydropyrans
Cooper, Dennis A.,Robbins, Emma,Tizzard, Graham J.,Coles, Simon J.,O'Brien, Matthew
, p. 3441 - 3455 (2017/04/13)
Combining the desymmetrization of a prochiral bis-hydroxymethyl group with the epimerization of a chiral furanyl ether in a single transformation, high levels of double diastereoselectivity have been achieved in a synthesis of 2,4,5-trisubstituted tetrahy
