143868-31-9Relevant academic research and scientific papers
Asymmetric synthesis of diastereomerically and enantiomerically pure α-amino-γ-nitro carboxylic esters via Michael addition of the titanated bislactim ether of cyclo (-L-Val-Gly-) to nitroolefines
Busch, Karla,Groth, Ulrich M.,Kuehnle, Wulf,Schoellkopf, Ulrich
, p. 5607 - 5618 (2007/10/02)
The titanated bislactim ethers of cyclo(-L-Val-Gly-) 3 and 7 were added highly diastereoselectively in a 1,4-fashion to the nitro olefines 4 yielding the nitro compounds 5. Upon acidic hydrolysis these nitro compounds 5 afforded the α-amino-γ-nitro acid e
