14387-17-8

Basic information

• Product Name: 3,5-di-tert-butyl-4-hydroxybenzyl acetate
• Synonyms: 3,5-di-tert-butyl-4-hydroxybenzyl acetate;3,5-Bis(1,1-dimethylethyl)-4-hydroxybenzenemethanol 1-acetate;Acetic acid 3,5-di-tert-butyl-4-hydroxybenzyl ester;Einecs 238-357-1
• CAS NO: 14387-17-8
• Molecular Formula: C₁₇H₂₆O₃
• Molecular Weight: 278.38654
• EINECS: 238-357-1
• Mol File: 14387-17-8.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 322.2°Cat760mmHg
• Flash Point: 116.4°C
• Appearance: /
• Density: 1.015g/cm³
• Vapor Pressure: 0.000151mmHg at 25°C
• Refractive Index: 1.501
• CAS DataBase Reference: 3,5-di-tert-butyl-4-hydroxybenzyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-di-tert-butyl-4-hydroxybenzyl acetate(14387-17-8)
• EPA Substance Registry System: 3,5-di-tert-butyl-4-hydroxybenzyl acetate(14387-17-8)

Safety Data

• Hazardous Substances Data: 14387-17-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H26O3/c1-11(18)20-10-12-8-13(16(2,3)4)15(19)14(9-12)17(5,6)7/h8-9,19H,10H2,1-7H3

Upstream product

• 108-24-7 acetic anhydride 
• 88-27-7 N,N-dimethyl-(3,5-di-tert-butyl-4-hydroxybenzyl)amine 
• 128-37-0 2,6-di-tert-butyl-4-methyl-phenol 
• 7726-95-6 bromine 
• 64-19-7 acetic acid 
• 88-26-6 3,5-di-tert-butyl-4-hydroxybenzyl alcohol 
• 128-39-2 2,6-di-tert-butylphenol 
• 50-00-0 formaldehyd 
• 955-01-1 3,5-di-tert-butyl-4-hydroxy benzyl chloride 
• 1620-98-0 3,5-di-t-butyl-4-hydroxybenzaldehyde 
• 6485-57-0 2,6-di-tert-butyl-4-hydroperoxy-4-methyl-2,5-cyclohexadienone 
• 10396-80-2 2,6-di-tert-butyl-4-hydroxy-4-methylcyclohexa-2,5-dienone 
• 752-60-3 tris-(3,5-di-tert-butyl-4-hydroxybenzyl)-amine 
• 13154-59-1 4-acetoxy-3,5-di-t-butylbenzyl acetate 

Downstream Products

• 127900-99-6 4-hydroxy-3,5-di-tert-butylbenzoxy acetic acid 
• 127901-00-2 glycolic acid 4-hydroxy-3,5-di-tert-butylbenzyl ester 
• 980-17-6 diisopropyl (3,5-di-tert-butyl-4-hydroxybenzyl)phosphonate 
• 10193-93-8 dibutyl (3,5-di-tert-butyl-4-hydroxybenzyl)phosphonate 
• 62267-59-8 2,4-di-tert-butyl-6-(3,5-di-tert-butyl-4-hydroxybenzyl)phenol 
• 6922-60-7 4,4'-(oxybis(methylene))bis(2,6-di-tert-butylphenol) 
• 752-60-3 tris-(3,5-di-tert-butyl-4-hydroxybenzyl)-amine 
• 118-82-1 4,4'-Methylenebis(2,6-di-tert-butylphenol) 
• 1709-70-2 1,3,5-trimethyl-2,4,6-tris-(3,5-di-tert-butyl-4-hydroxybenzyl)benzene 
• 41642-52-8 1,3,5-trimethyl-2,4-di(3,5-di-tert-butyl-4-hydroxybenzyl)benzene 
• 976-56-7 diethyl 4-hydroxy-3,5-di-tert-butylbenzylphosphonate 
• 55582-33-7 2,2-di-<4'-hydroxy-3',5'-di(4''-hydroxy-3'',5''-di-tert-butylbenzyl)phenyl>propane 
• 87-97-8 2,6-di-tert-butyl-4-methoxymethylene-phenol 

Relevant articles and documents

Oxidation by Cobalt(III) Acetate. Part 13. Oxidation of Substituted Phenols with Cobalt(III) Acetate in Acetic Acid

The oxidation of 2,6-di- and 2,4,6-tri-substituted phenols with cobalt(III) acetate has been investigated in acetic acid under an inert atmosphere; the former gave the corresponding diphenoquinones in excellent yields, and the latter yielded side-chain or nuclear acetoxylated products in moderate to good yields.

GREEN AND ATOM-ECONOMICAL PROCESSES FOR PRODUCING PHENOLIC ANTIOXIDANTS

Processes for producing 1,3,5-trimethyI-2,4,6-tris(3,5-dialkyl-4- hydroxybenzyl)benzene are provided, in particular such processes that utilize 2,6-di-tert- butylphenol, paraformaldehyde, a secondary amine, mesitylene, and acetic acid.

Process for the preparation of diphosphonate derivatives

A process for the preparation of a compound of formula I, STR1 wherein R1 and R2 are independently C1-6 alkyl, R3 is hydroxy and R4 and R5 are independently C1-6 alkyl is disclosed. The process comprises reacting a compound of formula II, STR2 wherein R1, R2 and R3 are defined as in formula I and X is a leaving group, with a compound of formula III, STR3 wherein R4 and R5 are independently C1-6 alkyl, in the presence of a base.