143884-26-8Relevant articles and documents
Practical synthesis and evaluation of the biological activities of 1α,25-dihydroxyvitamin D3 antagonists, 1α,25- dihydroxyvitamin D3-26,23-lactams. Designed on the basis of the helix 12-folding inhibition hypothesis
Nakano, Yusuke,Kato, Yuko,Imai, Keisuke,Ochiai, Eiji,Namekawa, Jun-Ichi,Ishizuka, Seiichi,Takenouchi, Kazuya,Tanatani, Aya,Hashimoto, Yuichi,Nagasawa, Kazuo
, p. 2398 - 2406 (2007/10/03)
A practical synthetic route to novel vitamin D antagonists of DLAM (1α,25-dihydroxyvitamin D3-26,23-lactam) was developed from vitamin D2 via the 1,3-dipolar cycloaddition reaction as a key step. Six DLAM derivatives (24 compounds) w
VITAMIN D3 DERIVATIVES AND REMEDIES USING THE SAME
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Page 31, (2010/02/09)
A vitamin D3 derivative expressed by the following general formula (1) [wherein, R is a hydrogen atom or a methyl group, and A is a single bond, -CH2-, -CH=CH-, -CH2-CH=CH-, -CH=CH-CH=CH-, -C=C- or -CH2-C≡C-; an
An improved synthesis of 24,24-difluoro-1α,25-dihydroxy-vitamin D3 from vitamin D2
Ando,Kondo,Koike,Takayama
, p. 1662 - 1664 (2007/10/02)
An improved synthesis of a highly potent vitamin D3 analog, 24,24-difluoro-1α,25-dihydroxyvitamin D3 has been accomplished. The total yield was 9.3% from inexpensive vitamin D2 in 11 steps.