1438891-79-2

Upstream product

• 1438891-78-1 (2S,6S)-2,6-diphenyltetrahydro-2H-thiopyran 
• 295328-89-1 (R,R)-1,5-bis(methanesulfonyloxy)-1,5-diphenylpentane 
• 195443-92-6 (-)-(S,S)-1,5-diphenylpentane-1,5-diol 
• 6263-83-8 1,5-diphenyl-1,5-pentanedione 
• 2873-74-7 gloutaric dichloride 
• 108-55-4 glutaric anhydride, 

Relevant academic research and scientific papers

Methods for the synthesis of chiral sulfur heterocycles and their application in the asymmetric Baylis-Hillman reactions

Enantiomerically pure (2S,6S)-2,6-diphenyltetrahydro-2H-thiopyran, (2S)-2-phenyltetrahydro thiophene, and (2S)-2-phenyltetrahydro-2H-thiopyran were prepared in 70-72% yields and with 86-99% ee via cyclization of the corresponding dimesylate in an SN2 cyclization reaction using sodium sulfide nonahydrate. The results on the application of various chiral sulfides in asymmetric Baylis-Hillman reactions are also described.