1438893-38-9Relevant academic research and scientific papers
Synthesis of new 3-heteroaryl-2-phenylquinolines and their pharmacological activity as antimicrobial agents
Benzerka, Saida,Bouraiou, Abdelmalek,Bouacida, Sofiane,Roisnel, Thierry,Bentchouala, Chafia,Smati, Farida,Carboni, Bertrand,Belfaitah, Ali
, p. 94 - 99 (2013)
Some new unfused tricyclic aromatic systems containing various heterocyclic cores were synthesized. These compounds were prepared in good yields via appropriate routes using 6-methyl-2-phenylquinoline-3-carbaldehyde as a key intermediate. The antibacterial activity of the prepared compounds was evaluated against: Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumonia and Salmonella thipymurium using the disk-diffusion method. The minimum inhibitory concentration (MIC) was determined for the tested compounds.
