14389-12-9

Basic information

• Product Name: 5-(4-PYRIDYL)-1H-TETRAZOLE
• Synonyms: 5-(4-PYRIDYL)TETRAZOLE;5-(4-PYRIDYL)-1H-TETRAZOLE;4-(1H-1,2,3,4-tetraazol-5-yl)pyridine;Pyridyltetrazole;4-(1H-1,2,3,4-Tetraazol-5-yl)pyridine,97%;4-(1H-Tetrazol-5-yl)pyridine;5-(Pyridin-4-yl)-1H-tetrazole
• CAS NO: 14389-12-9
• Molecular Formula: C₆H₅N₅
• Molecular Weight: 147.14
• Mol File: 14389-12-9.mol
• Article Data: 81

Chemical Properties

• Melting Point: 265 °C
• Boiling Point: 390.341 °C at 760 mmHg
• Flash Point: 198.684 °C
• Appearance: /
• Density: 1.388 g/cm³
• Vapor Pressure: 2.67E-06mmHg at 25°C
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 6.92±0.10(Predicted)
• CAS DataBase Reference: 5-(4-PYRIDYL)-1H-TETRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-PYRIDYL)-1H-TETRAZOLE(14389-12-9)
• EPA Substance Registry System: 5-(4-PYRIDYL)-1H-TETRAZOLE(14389-12-9)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 22-36/37/39-36-26
• HazardClass: IRRITANT-HARMFUL
• Hazardous Substances Data: 14389-12-9(Hazardous Substances Data)

Usage

General Description

5-(4-Pyridyl)-1H-tetrazole is a chemical compound that belongs to the class of tetrazoles. It is a heterocyclic molecule containing both a pyridine ring and a tetrazole ring. 5-(4-PYRIDYL)-1H-TETRAZOLE is commonly used as a building block in organic chemistry and pharmaceutical research. It has been found to have potential applications in the synthesis of biologically active compounds and in drug development. Tetrazoles are known for their diverse pharmacological activities, making 5-(4-Pyridyl)-1H-tetrazole a valuable tool in the field of medicinal chemistry. Additionally, the presence of the pyridine ring in this compound may also contribute to its reactivity and properties in various chemical reactions.

InChI:InChI=1/C6H4N5/c1-3-7-4-2-5(1)6-8-10-11-9-6/h1-4H/q-1

Upstream product

• 100-48-1 pyridine-4-carbonitrile 
• 1692-15-5 4-pyridylboronic acid 
• 67-68-5 dimethyl sulfoxide 
• 15854-87-2 4-iodopyridine 

Downstream Products

• 70027-21-3 4-(2-(p-tolyl)-2H-tetrazol-5-yl)pyridine 
• 70027-23-5 4-[2-(4-chloro-phenyl)-2H-tetrazol-5-yl]-pyridine 
• 65452-72-4 4-(2-phenyl-2H-tetrazol-5-yl)pyridine 
• 58022-65-4 2-methyl-5-(pyridin-4-yl)-1,3,4-oxadiazole 
• 56353-00-5 4-(5-phenyl-1,3,4-oxadiazol-2-yl)pyridine 
• 89013-88-7 2-(4-methoxyphenyl)-5-(4-pyridyl)-1,3,4-oxadiazole 

Relevant articles and documents

1-Disulfo-[2,2-bipyridine]-1,1-diium chloride ionic liquid as an efficient catalyst for the green synthesis of 5-substituted 1H-tetrazoles

A simple, green and efficient method has been developed for the synthesis of 5-substituted 1H-tetrazole derivatives through [2+3] cycloaddition reaction in good to excellent yields between various benzonitriles and sodium azide. For this purpose, 1-disulfo-[2,2-bipyridine]-1,1-diium chloride ([BiPy](HSO3)2Cl2) system as an ionic liquid catalyst have been extended for the construction of these valuable products. This procedure has significant advantages, including using ethylene glycol as a green solvent. The other advantages of this method are inexpensive and ease the preparation of the catalyst, mild reaction conditions, green reaction medium, easy workup, short reaction time, and simple experimental process.

PROCESS FOR PREPARING 5-SUBSTITUTED-1H-TETRAZOLES IN AQUEOUS BETAINE SOLUTION

The present invention relates to a method for manufacturing 5-substituted-1H-tetrazole in an aqueous betaine solution. More specifically, the present invention relates to a method for manufacturing 5-substituted-1H-tetrazole which comprises: a step of con

Bivalent zinc ion metal organic complex as well as preparation method and application thereof (by machine translation)

The invention relates to a divalent zinc ion metal organic complex and a preparation method and application, and firstly, an organic ligand L, and a structural formula thereof are prepared firstly: The solution of the organic ligand L and the zinc salt solution react at room temperature to obtain the metal organic complex, and the metal organic complex serves as a catalyst to catalyze the synthesis of diisopropyl - D D-mannitol to have a good catalytic effect. (by machine translation)