14389-77-6Relevant articles and documents
Preparation of highly enantiopure β-amino esters by Candida antarctica lipase A
Gedey, Szilvia,Liljeblad, Arto,Lazar, Laszlo,Fueloep, Ferenc,Kanerva, Liisa T.
, p. 105 - 110 (2001)
The enantioselectivities for the reactions of aliphatic β-substituted β-amino esters [RCH(NH2)CH2CO2Et with R = Me, Et, n-Pr, i-Pr, CHEt2, cyclohexyl and Ph] with butyl butanoate in neat butyl butanoate and with 2,2,2-trifluoroethyl butanoate in diisopropyl ether were studied in the presence of Candida antarctica lipase A. Enantioselectivities ranging from good (E = 70-100) to excellent (E>100) were commonly observed, allowing gram-scale resolution of the substrates.
Enantioselektive Synthese von β-Aminosaeuren - TMS-SAMP als chirales Ammoniak-Aequivalent in der azaanalogen Michael-Addition an α,β-ungesaettigte Ester
Enders, Dieter,Wahl, Heiner,Bettray, Wolfgang
, p. 527 - 529 (2007/10/02)
Stichworte: Aminosaeuren * Asymmetrische Synthesen * Chirale Hilfsstoffe * Michael-Additionen