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(2,2-dimethyl-4-phenyl-butyl) N-[(2S,3R)-2-methyl-4-oxooxetan-3-yl]carbamate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1439366-69-4

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1439366-69-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1439366-69-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,3,9,3,6 and 6 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1439366-69:
(9*1)+(8*4)+(7*3)+(6*9)+(5*3)+(4*6)+(3*6)+(2*6)+(1*9)=194
194 % 10 = 4
So 1439366-69-4 is a valid CAS Registry Number.

1439366-69-4Downstream Products

1439366-69-4Relevant academic research and scientific papers

Disubstituted beta-lactones as inhibitors of N-acylethanolamine acid amidase (NAAA)

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, (2016/06/28)

The present invention provides compounds and pharmaceutical compositions for inhibiting N-acylethanolamine acid amidase (NAAA). Inhibition of NAAA is contemplated as a method to sustain the levels of palmitoylethanolamide (PEA) and oleylethanolamide (OEA), two substrates of NAAA, in conditions characterized by reduced concentrations of PEA and OEA. The invention also provides methods for treating inflammatory diseases and pain, and other disorders in which decreased levels of PEA and OEA are associated with the disorder.

Synthesis, biological evaluation, and 3D QSAR study of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters as N -acylethanolamine acid amidase (NAAA) inhibitors

Ponzano, Stefano,Berteotti, Anna,Petracca, Rita,Vitale, Romina,Mengatto, Luisa,Bandiera, Tiziano,Cavalli, Andrea,Piomelli, Daniele,Bertozzi, Fabio,Bottegoni, Giovanni

, p. 10101 - 10111 (2015/02/02)

N-(2-Oxo-3-oxetanyl)carbamic acid esters have recently been reported to be noncompetitive inhibitors of the N-acylethanolamine acid amidase (NAAA) potentially useful for the treatment of pain and inflammation. In the present study, we further explored the

DISUBSTITUTED BETA-LACTONES AS INHIBITORS OF N-ACYLETHANOLAMINE ACID AMIDASE (NAAA)

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, (2013/06/06)

The present invention provides compounds and pharmaceutical compositions for inhibiting N-acylethanolamine acid amidase (NAAA). Inhibition of NAAA is contemplated as a method to sustain the levels of palmitoylethanolamide (PEA) and oleylethanolamide (OEA), two substrates of NAAA, in conditions characterized by reduced concentrations of PEA and OEA. The invention also provides methods for treating inflammatory diseases and pain, and other disorders in which decreased levels of PEA and OEA are associated with the disorder.

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