1439388-07-4Relevant academic research and scientific papers
A new [2+2+1] heterocyclization for the synthesis of 2,3,5-trisubstituted thiophenes under microwave irradiation
Xu, Hai-Wei,Ma, Guan-Hua,Jiang, Bo,Tu, Shu-Jiang
, p. 3392 - 3398 (2014/01/06)
A new three-component strategy for the efficient synthesis of 2,3,5-trisubstituted thiophene derivatives through a [2+2+1] heterocyclization between 3-(2-aryl-2-oxoethylidene)-2-oxindoles and α-thiocyanato ketones under microwave irradiation is described.
An aquatic pseudo-four-component reaction for the synthesis of highly substituted thiophenes
Zali-Boeini, Hassan,Ghani, Maryam
, p. 913 - 918 (2013/05/08)
A novel and simple procedure was developed for the construction of fully substituted thiophenes. A series of α-haloacetophenone derivatives were converted into fully substituted thiophenes by treatment with sodium sulfide in the presence of 1,8-diazabicyc
