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143946-49-0

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143946-49-0 Usage

General Description

Quinoline, 4-chloro-5,7-dimethoxy- is a chemical compound with a quinoline backbone and chloro- and methoxy- substituents. It is a heterocyclic organic compound that has a variety of applications. It is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various drugs and also as a building block in the development of new compounds. It may also have some industrial and research applications, although its specific uses may vary. Quinoline, 4-chloro-5,7-dimethoxy- has a yellowish color and a distinct odor, and its properties and reactivity make it an important molecule in the field of organic chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 143946-49-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,9,4 and 6 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 143946-49:
(8*1)+(7*4)+(6*3)+(5*9)+(4*4)+(3*6)+(2*4)+(1*9)=150
150 % 10 = 0
So 143946-49-0 is a valid CAS Registry Number.

143946-49-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-chloro-5,7-dimethoxyquinoline

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:143946-49-0 SDS

143946-49-0Relevant articles and documents

Aurora Kinase Modulators and Method of Use

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Paragraph 0478; 0494, (2014/11/27)

The present invention relates to chemical compounds having a general formula I wherein A1-8, D′, L1, L2, R1, R6-8 and n are defined herein, and synthetic intermediates, which are capable of modulating various protein kinase receptor enzymes and, thereby, influencing various disease states and conditions related to the activities of such kinases. For example, the compounds are capable of modulating Aurora kinase thereby influencing the process of cell cycle and cell proliferation to treat cancer and cancer-related diseases. The invention also includes pharmaceutical compositions, including the compounds, and methods of treating disease states related to the activity of Aurora kinase.

QUINOLINE DERIVATIVES

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Page/Page column 41, (2009/04/24)

The invention concerns quinoline derivatives of Formula I or a pharmaceutically-acceptable salt thereof, wherein each of X1, p, R1, q, R2, R3, R4, R5Ring A, r and R6 has any of the meanings defined hereinbefore in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the treatment of cell proliferative disorders.

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