143951-10-4

Basic information

• Product Name: 2-phenyl-3-tetrahydrofurfuryl-6,11α-dimethyl-8-hydroxy-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine
• CAS NO: 143951-10-4
• Molecular Weight: 377.527
• Mol File: 143951-10-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-phenyl-3-tetrahydrofurfuryl-6,11α-dimethyl-8-hydroxy-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-3-tetrahydrofurfuryl-6,11α-dimethyl-8-hydroxy-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine(143951-10-4)
• EPA Substance Registry System: 2-phenyl-3-tetrahydrofurfuryl-6,11α-dimethyl-8-hydroxy-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine(143951-10-4)

Safety Data

• Hazardous Substances Data: 143951-10-4(Hazardous Substances Data)

Upstream product

• 116708-12-4 1-benzyl-2-cyano-3,4-dimethyl-2-(p-methoxybenzyl)-1,2,5,6-tetrahydropyridine 
• 116708-04-4 1-benzyl-2-phenyl-2-(p-methoxybenzyl)-3,4-dimethyl-1,2,5,6-tetrahydropyridine 
• 824-94-2 p-methoxybenzyl chloride 
• 100-58-3 phenylmagnesium bromide 
• 116708-09-9 2-phenyl-3-benzyl-6,11α-dimethyl-8-hydroxy-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine 
• 116708-14-6 1-Benzyl-3,4-dimethyl-1,2,5,6-tetrahydro-pyridine-2-carbonitrile 
• 1192-30-9 tetrahydrofurfuryl bromide 
• 143951-09-1 2-phenyl-6,11α-dimethyl-8-hydroxy-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine 

Relevant articles and documents

Synthesis of C-2 substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines: Binding studies on opioid receptors

The racemic C-2 substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines 8a-k were prepared in three steps from the readily available 2-cyano-1,2,5,6-tetrahydropyridines 4a-c. This involved alkylation of the anion of 4a-c with the appropriate alkyl ha