143953-89-3Relevant academic research and scientific papers
The Phospha-Cope Rearrangement of 3-Phospha-1,5-hexadiene Derivatives Bearing a Hydroxyl Group
Kawashima, Takayuki,Park, Dae Jong,Murata, Shinobu,Okazaki, Renji,Inamoto, Naoki
, p. 1607 - 1610 (2007/10/02)
The title phospha-Cope rearrangement gives the corresponding cyclic phosphonates or phosphinates in 30 to 100percent yield.Stugies on solvent effects and kinetic isotope effects using the deuterated derivatives strongly support that there is a pre-equilibrium between tetracoordinate and pentacoordinate structures, followed by the rate-determinig phospha-Cope rearrangement.
