14399-37-2 Usage
General Description
2-Amino-5-bromo-3-methoxypyrazine is a chemical compound with molecular formula C5H6BrN3O, which has a pyrazine ring structure. It is a brominated and methoxylated derivative of pyrazine and is used as a flavoring agent. It is commonly found in food products such as coffee, cocoa, and roasted nuts, where it contributes to the overall aroma and taste profile. The compound has a strong earthy and musty odor, with some slightly sweet and fruity notes. It is also used in the fragrance industry to add a green and earthy character to perfumes and other scented products. Additionally, 2-Amino-5-bromo-3-methoxypyrazine has been studied for its potential biological activities, including its ability to act as an inhibitor of the enzyme glucose-6-phosphate dehydrogenase and its potential use as an anti-cancer agent.
Check Digit Verification of cas no
The CAS Registry Mumber 14399-37-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,3,9 and 9 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 14399-37:
(7*1)+(6*4)+(5*3)+(4*9)+(3*9)+(2*3)+(1*7)=122
122 % 10 = 2
So 14399-37-2 is a valid CAS Registry Number.
InChI:InChI=1S/C5H6BrN3O/c1-10-5-4(7)8-2-3(6)9-5/h2H,1H3,(H2,7,8)
14399-37-2Relevant articles and documents
MANUFACTURE OF COMPOUNDS AND COMPOSITIONS FOR INHIBITING ACTIVITY OF SHP2
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Paragraph 00155-00156, (2022/02/06)
Provided herein is a method for the manufacture of a compound of Formula I or a pharmaceutically acceptable salt, acid co-crystal, hydrate or other solvate thereof, said method comprising reacting a compound of the formula II with a compound of the formula III according to the following reaction scheme, wherein LG, A, n, m and p are as defined in the Summary of the Invention, said manufacture including the manufacture and use of a compound of the formula VI, wherein R1 is a secondary amino protecting group and R5 is unsubstituted or substituted alkyl, unsubstituted or substituted cycloalkyl or unsubstituted or substituted aryl.
PROCESS OF MANUFACTURE OF A COMPOUND FOR INHIBITING THE ACTIVITY OF SHP2
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Paragraph 00316; 00317; 00323; 00324, (2020/05/12)
The invention relates to a method for the manufacture of a compound of Formula I as mentioned above, or a pharmaceutically acceptable salt, acid co-crystal, hydrate or other solvate thereof, said method comprising reacting a compound of the formula II wit
