14399-37-2 Usage
Uses
Used in Flavoring Industry:
2-Amino-5-bromo-3-methoxypyrazine is used as a flavoring agent in the food industry, particularly enhancing the aroma and taste profile of products such as coffee, cocoa, and roasted nuts. Its unique combination of earthy, musty, and slightly sweet notes contributes to the rich sensory experience of these food items.
Used in Fragrance Industry:
In the fragrance industry, 2-Amino-5-bromo-3-methoxypyrazine is employed to impart a green and earthy character to perfumes and other scented products. Its distinct aromatic profile adds depth and complexity to the overall scent, making it a valuable component in creating unique and appealing fragrances.
Used in Pharmaceutical Research:
2-Amino-5-bromo-3-methoxypyrazine has been studied for its potential biological activities, including its ability to act as an inhibitor of the enzyme glucose-6-phosphate dehydrogenase. This property makes it a subject of interest in pharmaceutical research, where it could potentially be developed into a therapeutic agent for certain conditions.
Used in Anti-Cancer Research:
Furthermore, 2-Amino-5-bromo-3-methoxypyrazine has shown promise in anti-cancer research, indicating its potential use as an anti-cancer agent. Its specific biological activities and interactions with cellular processes are areas of ongoing investigation, with the aim of understanding its full therapeutic potential in combating cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 14399-37-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,3,9 and 9 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 14399-37:
(7*1)+(6*4)+(5*3)+(4*9)+(3*9)+(2*3)+(1*7)=122
122 % 10 = 2
So 14399-37-2 is a valid CAS Registry Number.
InChI:InChI=1S/C5H6BrN3O/c1-10-5-4(7)8-2-3(6)9-5/h2H,1H3,(H2,7,8)
14399-37-2Relevant academic research and scientific papers
MANUFACTURE OF COMPOUNDS AND COMPOSITIONS FOR INHIBITING ACTIVITY OF SHP2
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Paragraph 00155-00156, (2022/02/06)
Provided herein is a method for the manufacture of a compound of Formula I or a pharmaceutically acceptable salt, acid co-crystal, hydrate or other solvate thereof, said method comprising reacting a compound of the formula II with a compound of the formula III according to the following reaction scheme, wherein LG, A, n, m and p are as defined in the Summary of the Invention, said manufacture including the manufacture and use of a compound of the formula VI, wherein R1 is a secondary amino protecting group and R5 is unsubstituted or substituted alkyl, unsubstituted or substituted cycloalkyl or unsubstituted or substituted aryl.
MANUFACTURE OF COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2
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Paragraph 00227-00228; 00233, (2020/05/12)
The present invention relates to a method for the manufacture of a compound of Formula I or a pharmaceutically acceptable salt, acid co-crystal, hydrate or other solvate thereof, said method comprising reacting a compound of the formula II with a compound of the formula III according to the following reaction scheme: wherein LG, A, n, m and p are as defined in the Summary of the Invention.
PROCESS OF MANUFACTURE OF A COMPOUND FOR INHIBITING THE ACTIVITY OF SHP2
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Paragraph 00316; 00317; 00323; 00324, (2020/05/12)
The invention relates to a method for the manufacture of a compound of Formula I as mentioned above, or a pharmaceutically acceptable salt, acid co-crystal, hydrate or other solvate thereof, said method comprising reacting a compound of the formula II wit
