143997-01-7

Upstream product

• 112-80-1 cis-Octadecenoic acid 
• 143996-95-6 (Z)-Octadec-9-enoic acid (R)-2-hydroxy-3-(4-methoxy-benzyloxy)-propyl ester 
• 80910-01-6 (S)-2-[(4-methoxybenzyloxy)methyl]oxirane 
• 105-13-5 4-Methoxybenzyl alcohol 
• 109786-74-5 (R)-3-(4-methoxybenzyloxy)propane-1,2-diol 
• 109786-73-4 (S)-4-[(4-methoxybenzyloxy)methyl]-2,2-dimethyl-1,3-dioxolane 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 2465-32-9 1,3-diolein 
• 24529-88-2 1,2-dioleoyl-sn-glycerol 
• 62700-69-0 L-α-dioleoylphosphatidylglycerol 
• 4235-95-4 dioleoylphosphatidylcholine 

Relevant academic research and scientific papers

Stereospecific synthesis of phosphatidylglycerol using a cyanoethyl phosphoramidite precursor

Phosphatidylglycerols (PG) are a family of naturally occurring phospholipids that are responsible for critical operations within cells. PG are characterized by an (R) configuration in the diacyl glycerol backbone and an (S) configuration in the phosphoglycerol head group. Herein, we report a synthetic route to provide control over the PG stereocenters as well as control of the acyl chain identity.

A Convenient Synthesis of Platelet-Activating Factors and Their Analogues from Chiral Epichlorohydrin

Two platelet activating factors (PAF) were conveniently prepared from optically active epichlorohydrin via 5 steps in 15-16percent total yield.Four analogues containing oleoyl, propyl, p-trifluoromethylphenoxy, and N,N-dimethyldithiocarbamoyl groups were also prepared.