144010-82-2Relevant academic research and scientific papers
Synthesis of Novel C-Pivot Lariat 18-Crown-6 Ethers and Their Efficient Purification
Jana, Susovan,Suresh, Vallabh,Lepore, Salvatore D.
, p. 1977 - 1980 (2015)
The syntheses of various lariat ethers including several not previously reported and their efficient purification are presented. The synthesis route brings together reactions from a variety of previous works leading to a robust and generalized approach to these C-pivot lariats. The main steps are condensation of functionalized diols with pentaethylene glycol ditosylate in the presence of potassium as a templating cation. Purification of the final products was achieved without chromatography by extracting from an aqueous potassium hydroxide solution.
Studies toward the synthesis of iejimalides A-D: Preparation of the C3-11 and C12-C24 fragments
Sabitha, Gowravaram,Gurumurthy,Yadav, Jhillu Singh
, p. 110 - 118 (2014/01/06)
The convergent synthesis of the C3-C11 and C12-C24 fragments of the iejimalides A-D is described. The C3-C11 fragment is obtained by a cross-metathesis reaction, while the C12-C24 fragment is derived from a Still-Gennari modified Horner-Wadsworth-Emmons o
An expedient procedure for the oxidative cleavage of olefinic bonds with PhI(OAc)2, NMO, and Catalytic OsO4
Nicolaou,Adsool, Vikrant A.,Hale, Christopher R. H.
supporting information; experimental part, p. 1552 - 1555 (2010/06/16)
(Figure Presented) PhI(OAc)2 In the presence of OsO4 (cat.) and 2,6-lutidine cleaves oleflnlc bonds to yield the corresponding carbonyl compounds, albeit, In some cases, with a-hydroxy ketones as byproduct. A more practical and clean protocol to effect oxidative cleavage of olefinic bonds involves NMO, OsO4 (cat.), 2,6-lutidine, and PhI(OAc) 2.
