1440337-93-8Relevant articles and documents
A tandem strategy for the synthesis of 1H-benzo[g]indazoles and naphtho[2,1-d]isoxazoles from o-alkynylarene chalcones
Akbar, Sikkandarkani,Srinivasan, Kannupal
, p. 1663 - 1666 (2013)
o-Alkynylarene chalcones when treated with hydrazines and hydroxylamine in the presence of iodine gave 1H-benzo[g]indazoles and naphtho[2,1-d]isoxazoles, respectively. The transformations involve tandem oxidative cyclocondensation/ electrophilic hydroarylation. The methodology was applied to quinoline-based chalcones, which also afforded the corresponding quinoline-fused benzindazole and benzisoxazole. o-Alkynylarene chalcones undergo tandem oxidative cyclocondensation/electrophilic hydroarylation with arylhydrazines and hydroxylamine in the presence of iodine to afford 1H-benzo[g]indazoles and naphtho[2,1-d]isoxazoles, respectively. Copyright