1440422-65-0Relevant academic research and scientific papers
Base-promoted, CBr4-mediated tandem bromination/intramolecular Friedel-Crafts alkylation ofN-aryl enamines: a facile access to 1H- And 3H-indoles
Li, Fangyi,Li, Zheng,Qiu, Changfu,Wang, Chunhua,Yin, Guangwei,Zhao, Lan,Zhao, Lixin
, p. 5377 - 5382 (2021)
Described here is a general and highly efficient method for the synthesis of 1H- and 3H-indoles. In the presence of CBr4and a suitable base, the cyclization ofN-aryl enamines proceeds with high efficiency. Unlike previous intramolecular cross d
Copper-Mediated One-Pot Synthesis of Indoles through Sequential Hydroamination and Cross-Dehydrogenative Coupling Reaction
Cai, Yichao,Chen, Chunxia,Chen, Xin,Liu, Yajie,Peng, Jinsong,Song, Zirui,Sun, Peng,Yang, Jiaojiao
, p. 75 - 84 (2019/12/26)
Starting from simple anilines and ester arylpropiolates, an efficient one-pot synthesis of 2-arylindole-3-carboxylate derivatives has been developed through copper-mediated sequential hydroamination and cross-dehydrogenative coupling (CDC) reaction. The i
Iodide-Ion-Catalyzed carbon-carbon bond-forming cross-dehydrogenative coupling for the synthesis of indole derivatives
Jia, Zhenhua,Nagano, Takashi,Li, Xingshu,Chan, Albert S. C.
supporting information, p. 858 - 861 (2013/03/14)
The nBu4NI-catalyzed intramolecular cross-dehydrogenative coupling (CDC) reaction has been applied to the synthesis of 1H-indole derivatives. Intramolecular oxidative coupling of N-arylenamines proceeded in the presence of a catalytic amount of nBu4NI and tert-butyl hydroperoxide (TBHP) to afford the corresponding 1H-indole derivatives in good-to-excellent yields. A preliminary study of the synthesis of 3H-indole is also reported. This is a rare example of the nBu4NI-catalyzed C-C bond-forming CDC reaction. Copyright
