1440422-72-9Relevant academic research and scientific papers
Iodide-Ion-Catalyzed carbon-carbon bond-forming cross-dehydrogenative coupling for the synthesis of indole derivatives
Jia, Zhenhua,Nagano, Takashi,Li, Xingshu,Chan, Albert S. C.
, p. 858 - 861 (2013)
The nBu4NI-catalyzed intramolecular cross-dehydrogenative coupling (CDC) reaction has been applied to the synthesis of 1H-indole derivatives. Intramolecular oxidative coupling of N-arylenamines proceeded in the presence of a catalytic amount of nBu4NI and tert-butyl hydroperoxide (TBHP) to afford the corresponding 1H-indole derivatives in good-to-excellent yields. A preliminary study of the synthesis of 3H-indole is also reported. This is a rare example of the nBu4NI-catalyzed C-C bond-forming CDC reaction. Copyright
