1440430-16-9

Upstream product

• 123743-14-6 2,3-dihydro-2-(2-methoxyphenyl)-4H-1-benzopyran-4-one 
• 68-12-2 N,N-dimethyl-formamide 
• 42220-77-9 1-(2-hydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one 
• 135-02-4 ortho-anisaldehyde 
• 118-93-4 o-hydroxyacetophenone 

Downstream Products

• 1440429-57-1 (2S,1'R)-4-chloro-3-(1'-hydroxypropyl)-2-(2'-methoxyphenyl)-2H-chromene 

Relevant academic research and scientific papers

Asymmetric preparation of new N, N -dialkyl-2-amino-1,1,2-triphenylethanol catalysts and a kinetic resolution in the addition of diethylzinc to flavene-3-carbaldehydes

Enantiopure N,N-dialkyl-(S)-2-amino-1,1,2-triphenylethanols were prepared using a new synthetic methodology and tested for their ability to catalyze the enantioselective addition of diethylzinc to aldehydes. The structural modification of N-substituents of the catalysts led us to identify N-methyl-N-(S)-1-phenyl-ethyl-substituted 4d as an effective catalyst for the addition. Also disclosed is a kinetic resolution of racemic flavene-3- carbaldehydes with the chiral catalyst.