1440513-49-4Relevant articles and documents
Transition metal-free α-C(sp3)-H bond functionalization of amines by oxidative cross dehydrogenative coupling reaction: Simple and direct access to C-4-alkylated 3,4-dihydroquinazoline derivatives
Kumar, R. Arun,Saidulu,Prasad, K. Rajendra,Kumar, G. Sathish,Sridhar,Reddy, K. Rajender
supporting information, p. 2985 - 2991 (2013/01/15)
A transition metal-free catalytic system has been developed for the cross dehydrogenative coupling of amines with nitroalkanes under mild condition employing potassium iodide/tert-butyl hydrogen peroxide catalytic system. This methodology was further extended for the construction of biologically important N-heterocycles, namely, 3,4-dihydroquinazoline derivatives. This novel strategy provides a simple, efficient, and direct access to 4-alkyl-3,4- dihydroquinazoline derivatives. Copyright