1440529-79-2Relevant academic research and scientific papers
Organocatalytic asymmetric annulation of 1,3-bis(alkoxycarbonyl)buta-1,3- dienes and aldehydes
Pezzati, Bernardo,Chellat, Mathieu F.,Murphy, John J.,Besnard, Celine,Reginato, Gianna,Stephens, John C.,Alexakis, Alexandre
, p. 2950 - 2953 (2013)
Asymmetric organocatalytic annulation of E/Z isomeric mixtures of bis(alkyl carboxylate)buta-1,3-dienes and aldehydes has been realized via enamine catalysis. In the presence of α,α-diphenyl-2-pyrrolidinemethanol trimethylsilyl ether, excellent stereo- and enantioselectivities were achieved for a broad spectrum of substrates.
