144060-40-2 Usage
Uses
Used in Pharmaceutical Industry:
Febuxostat Bromo Impurity is used as an impurity in the production of Febuxostat, which is a xanthine oxidase/xanthine dehydrogenase inhibitor. The primary application of Febuxostat Bromo Impurity is for the treatment of hyperuricemia and chronic gout. It has been proven effective in lowering serum urate levels when administered at a dosage of 40-120 mg/day to manage hyperuricemia in patients with gout.
Check Digit Verification of cas no
The CAS Registry Mumber 144060-40-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,0,6 and 0 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 144060-40:
(8*1)+(7*4)+(6*4)+(5*0)+(4*6)+(3*0)+(2*4)+(1*0)=92
92 % 10 = 2
So 144060-40-2 is a valid CAS Registry Number.
144060-40-2Relevant academic research and scientific papers
2-arylthiazole derivatives and pharmaceutical composition thereof
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, (2008/06/13)
Pharmaceutical compositions for treating gout or hyperuricemia and containing a new categorized compound, i.e. 2-arylthiazole derivatives, as an active ingredient, are provided. The 2-arylthiazole derivatives in the present invention are represented by the following formula (I): STR1 wherein Ar is an unsubstituted or substituted pyridyl, thienyl, furyl, naphthyl or phenyl group; X is a hydrogen atom, alkyl group or carboxyl group which may be protected, and Y is a hydrogen atom, alkyl group, or a hydroxyl or carbonyl group which may be protected. Furthermore, novel compounds included in the 2-arylthiazole derivatives and pharmaceutically acceptable salts thereof are provided.
