144067-48-1

Basic information

• Product Name: 2,10-Dioxo-12,15,15-trimethyltricyclo[9.3.1.0^3,8]pentadec-11-ene
• CAS NO: 144067-48-1
• Molecular Weight: 274.403
• Mol File: 144067-48-1.mol

Chemical Properties

• CAS DataBase Reference: 2,10-Dioxo-12,15,15-trimethyltricyclo[9.3.1.0^3,8]pentadec-11-ene(CAS DataBase Reference)
• NIST Chemistry Reference: 2,10-Dioxo-12,15,15-trimethyltricyclo[9.3.1.0^3,8]pentadec-11-ene(144067-48-1)
• EPA Substance Registry System: 2,10-Dioxo-12,15,15-trimethyltricyclo[9.3.1.0^3,8]pentadec-11-ene(144067-48-1)

Safety Data

• Hazardous Substances Data: 144067-48-1(Hazardous Substances Data)

Upstream product

• 144067-39-0 1-((E)-6-Iodo-1-oxohex-2-enyl)-2,6,6-trimethyl-5-(1-oxoprop-2-enyl)cyclohex-1-ene 

Relevant articles and documents

A tandem radical macrocyclisation-transannular cyclisation approach towards the taxanes

Separate treatment of the iodotrienedione 19 and the iododienynedione 38 with Bu3SnH-AIBN produces the corresponding taxane ring systems 25 (25-30%) and 56 (50-60%) respectively by way of tandem radical macrocyclisation-radical transannular cyc

A tandem radical macrocyclisation - Radical transannulation strategy to the taxane ring system

Treatment of the iodo-trienone (8 b) with tri-n-butyltin hydride in the presence of AIBN is shown to produce the taxane ring system (11) by way of a tandem radical macrocyclisation - radical transannulation sequence, i.e. (8 b) → (9) → (11) (cf. Scheme 1)