1440870-07-4Relevant academic research and scientific papers
Stereocontrolled total synthesis of (+)-UCS1025A
Uchida, Kenji,Ogawa, Takahiro,Yasuda, Yoshinori,Mimura, Hiraku,Fujimoto, Teppei,Fukuyama, Tohru,Wakimoto, Toshiyuki,Asakawa, Tomohiro,Hamashima, Yoshitaka,Kan, Toshiyuki
, p. 12850 - 12853 (2013/02/23)
Under control: A stereocontrolled total synthesis of (+)-UCS1025A, a potent telomerase inhibitor, was achieved. The synthesis features an intramolecular Diels-Alder reaction, a tandem Staudinger/aza-Wittig reaction, and stereoselective construction of the hemiaminal moiety facilitated by neighboring-group participation. Copyright
