144095-45-4Relevant academic research and scientific papers
Chemical process for making angiotesin II antagonist compounds
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, (2008/06/13)
The invention provides a novel chemical process for the manufacture of quinoline, pyridine and imidazole derivatives of the formula IV wherein Q, Y 1 and Y 2 have the various meanings defined herein, and their non-toxic salts, which are angiotensin II inhibitors. The process involves the removal of an electron-deficient phenyl group or a pyridyl or pyrimidyl group from a compound of the formula VI as defined herein.
Heterocyclic boron compounds as intermediates for angiotensin II antagonists
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, (2008/06/13)
The invention concerns novel boron compounds of the formula IV, in which Q, Y 1, G 1 and G 2 have the various meanings defined herein, and their acid and base addition salts. The said compounds are useful in the manufacture of certain quinoline, pyridine and imidazole derivatives which have angiotensin II inhibitory activity. The invention also provides novel processes for the production of the quinoline, pyridine and imidazole derivatives. STR1
