1440960-67-7

Basic information

• Product Name: 2-Azaspiro[3.3]heptane-2-carboxylic acid, 6-forMyl-, 1,1-diMethylethyl ester
• Synonyms: 2-Azaspiro[3.3]heptane-2-carboxylic acid, 6-forMyl-, 1,1-diMethylethyl ester;tert-butyl 2-Formyl-6-azaspiro[3.3]heptane-6-carboxylate;tert-butyl 6-formyl-2-azaspiro[3.3]heptane-2-carboxylate;6-Formyl-2-aza-spiro[3.3]heptane-2-carboxylic acid tert-butyl ester;tert-butyl 2-Formyl-6-azaspiro[3.3]heptane-6-carboxylate - F11069
• CAS NO: 1440960-67-7
• Molecular Formula: C12H19NO3
• Molecular Weight: 225.28416
• Mol File: 1440960-67-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 318.7±42.0 °C(Predicted)
• Appearance: /
• Density: 1.13±0.1 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: -1.28±0.40(Predicted)
• CAS DataBase Reference: 2-Azaspiro[3.3]heptane-2-carboxylic acid, 6-forMyl-, 1,1-diMethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Azaspiro[3.3]heptane-2-carboxylic acid, 6-forMyl-, 1,1-diMethylethyl ester(1440960-67-7)
• EPA Substance Registry System: 2-Azaspiro[3.3]heptane-2-carboxylic acid, 6-forMyl-, 1,1-diMethylethyl ester(1440960-67-7)

Safety Data

• Hazardous Substances Data: 1440960-67-7(Hazardous Substances Data)

Usage

Description

2-Azaspiro[3.3]heptane-2-carboxylic acid, 6-forMyl-, 1,1-diMethylethyl ester, commonly known as tazobactam, is a synthetic β-lactamase inhibitor used in combination with piperacillin to treat bacterial infections. It functions by inhibiting the action of β-lactamase enzymes, which are produced by bacteria to inactivate β-lactam antibiotics such as penicillins and cephalosporins. Tazobactam enhances the activity of piperacillin, enabling it to effectively target a broader spectrum of bacteria.

Uses

Used in Pharmaceutical Industry:
2-Azaspiro[3.3]heptane-2-carboxylic acid, 6-forMyl-, 1,1-diMethylethyl ester is used as a β-lactamase inhibitor for the treatment of bacterial infections. It is combined with piperacillin to enhance its effectiveness against a wider range of bacteria, including those that produce β-lactamase enzymes. This combination is particularly useful in treating urinary tract, respiratory, and intra-abdominal infections caused by susceptible bacteria.
Used in Hospital Settings:
2-Azaspiro[3.3]heptane-2-carboxylic acid, 6-forMyl-, 1,1-diMethylethyl ester is used as an intravenous medication under the supervision of healthcare professionals in hospital settings. This ensures proper administration and monitoring of potential side effects, which may include diarrhea, rash, and allergic reactions.