1441061-95-5Relevant articles and documents
In vitro Anti-atherogenic Properties of N-Heterocyclic Carbene Aurate(I) Compounds
Sioriki, Eleni,Lordan, Ronan,Nahra, Fady,van Hecke, Kristof,Zabetakis, Ioannis,Nolan, Steven P.
, p. 2484 - 2487 (2018)
The anti-atherogenic (anti-inflammatory) properties of various aurate(I) salts, of the general formula [NHC?H][AuCl2] (NHC=N-heterocyclic carbene) were investigated. The aurates were easily synthesized and obtained in analytically pure form. In
Rapid and mild synthesis of Au-NHC complexes in a simple two-phase flow reactor
Fiksdahl, Anne,Harvie, Andrew J.,Jónsson, Helgi Freyr
, p. 7969 - 7975 (2021/06/21)
We describe a simple two-phase flow reactor which allows for the rapid synthesis of several Au(i)-NHC complexes in high yields (>88%), under mild conditions, and with minimal workup. Translation of the standard weak base method to a two-phase flow reaction prevents the common problem of decomposition to Au(0). The reaction can be scaled up more than ten-fold without loss in conversion efficiency. An optional second stage allows for direct synthesis of Au(iii)-NHC complexes, without isolation of the Au(i)-NHC intermediate, with a two-step isolated yield of 82%.