144147-65-9Relevant academic research and scientific papers
Tetrahydroindazole, tetrahydrocyclopentapyrazole, and hexahydrocycloheptapyrazole intermediate compounds
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, (2008/06/13)
Compounds of the general formula I: STR1 are disclosed as useful in the treatment or prevention of hypercholesterolemia, hyperlipoproteinemia and atherosclerosis. Novel intermediate compounds used to make the compound of formula I are also disclosed.
HMG-CoA Reductase Inhibitors: Design, Synthesis, and Biological Activity of Tetrahydroindazole-Substituted 3,5-Dihydroxy-6-heptenoic Acid Sodium Salts
Connolly, Peter J.,Westin, Claudia D.,Loughney, Deborah A.,Minor, Lisa K.
, p. 3674 - 3685 (2007/10/02)
Compounds comprising a series of 7--3,5-dihydroxy-6-heptenoic acid sodium salts (18) were synthesized and tested for their ability to inhibit HMG-CoA reductase in a partially purified enzyme preparati
TETRAHYDROINDAZOLE, TETRAHYDROCYCLOPENTAPYRAZOLE, AND HEXAHYDROCYCLOHEPTAPYRAZOLE COMPOUNDS AND THEIR USE AS HMG-COA REDUCTASE INHIBITORS
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, (2008/06/13)
Compounds of the general formula I: STR1 are disclosed as useful in the treatment or prevention of hypercholesterolemia, hyperlipoproteinemia and atherosclerosis. Novel intermediate compounds used to make the compound of formula I are also disclosed.
