144153-25-3

Upstream product

• 1184-85-6 N-methylmethane sulphonamide 
• 2216-94-6 phenylpropynoic acid ethyl ester 

Downstream Products

• 144153-31-1 6-Benzoyl-5-hydroxy-2-methyl-3-phenyl-2H-1,2-thiazin-1,1-dioxid 
• 144153-28-6 3,7-Diphenyl-6-hydroxy-2-methyl-5-oxo-2H,5H-1,2-thiazepin-1,1-dioxid 
• 144153-27-5 5,6-Dihydro-3,6-diphenyl-2-methyl-5-oxo-6-spiro-2'-oxiran-2H-1,2-thiazin-1,1-dioxid 
• 144153-29-7 3,7-Diphenyl-6-methoxy-2-methyl-5-oxo-2H,5H-1,2-thiazepin-1,1-dioxid 
• 144153-30-0 5-Benzoyloxy-2-methyl-3-phenyl-2H-1,2-thiazin-1,1-dioxid 
• 144153-26-4 6-Benzyliden-5,6-dihydro-2-methyl-3-phenyl-2H-1,2-thiazin-5-on-1,1-dioxid 

Relevant academic research and scientific papers

Synthesis of 1,2-thiazines and 1,2-thiazepines by ring expansion

The β-ketosultames 3 and 11 are transformed by aldol condensation into the corresponding alkylidene derivatives 4, 5 and 12. Epoxidation of 5 and 12 leads to the epoxyketones 6 and 13 which isomerize by boron trifluoride etherate to 1,2-thiazine 7 and 1,2