144154-58-5

Basic information

• Product Name: 2-(4-FLUOROSTYRYL)-1,3-BENZOXAZOLE
• Synonyms: 2-(4-FLUOROSTYRYL)-1,3-BENZOXAZOLE;2-[(E)-2-(4-fluorophenyl)ethenyl]-1,3-benzoxazole
• CAS NO: 144154-58-5
• Molecular Formula: C15H10FNO
• Molecular Weight: 239.24
• Mol File: 144154-58-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-FLUOROSTYRYL)-1,3-BENZOXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-FLUOROSTYRYL)-1,3-BENZOXAZOLE(144154-58-5)
• EPA Substance Registry System: 2-(4-FLUOROSTYRYL)-1,3-BENZOXAZOLE(144154-58-5)

Safety Data

• Hazardous Substances Data: 144154-58-5(Hazardous Substances Data)

Upstream product

• 95-21-6 2-methyl-1,3-benzoxazole 
• 459-57-4 4-fluorobenzaldehyde 
• 273-53-0 benzoxazole 
• 405-99-2 para-fluorostyrene 
• 41014-43-1 2-(chloromethyl)benzoxazole 

Relevant articles and documents

Diarylethene-based xerogels: The fabrication of more entangled networks driven by isomerization and acidofluorochromism

Fully-conjugated styrylbenzoxazoles and styrylbenzothiazoles of BOAF24, BOACl24, BOACl35, BOABr24, BOABr35, BTAF24, BTACl24 and BTABr24 without traditional gelation groups could form organogels. It was found that introduction of chlorine atoms in the 2,4-

Preparation method of 2-styrylbenzoxazole derivatives and application of 2-styrylbenzoxazole derivatives in anti-tumor effect

The invention discloses a structure and preparation method of 2-styrylbenzoxazole derivatives. 2-styrylbenzoxazole and different substituted aromatic aldehydes are taken as raw materials to react in one step under the anhydrous and oxygen-free conditions and the action of potassium tert-butoxide to generate 2-styrylbenzoxazole heterocyclic compounds. The preparation method has the advantages of being simple in reaction step, short in reaction time, good in selectivity and the like. In addition, the invention further provides research on application of an anti-tumor effect. The compounds 1, 2, 3 and 4 all show the certain bioactivity on in-vitro HepG2 cell proliferation inhibition, wherein the inhibition rate of the compound 1 on in-vitro HepG2 cell proliferation under the 100 micrometer concentration reaches 85.4%, and the inhibition rate of the compound 4 on in-vitro HepG2 cell proliferation under the 100 micrometer concentration reaches up to 93.4%.

A FACILE SYNTHESIS OF 2-(2'-SUBSTITUTED VINYL)BENZOXAZOLES

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