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1441769-24-9

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1441769-24-9 Usage

General Description

3-amino-5-chloro-1-methyl-2(1H)-Pyridinone, also known as 3-amino-5-chloro-1-methyl-2-pyridone, is a chemical compound with the molecular formula C6H7ClN2O. It is a heterocyclic compound containing a pyridine ring with an amino group at the 3-position and a chlorine atom at the 5-position. 3-amino-5-chloro-1-methyl-2(1H)-Pyridinone is commonly used as an intermediate or starting material in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is also known for its use as a building block in the production of various dyes and pigments. Additionally, 3-amino-5-chloro-1-methyl-2(1H)-Pyridinone has been studied for its potential biological activities, including antimicrobial and antiviral properties. Due to its versatile applications and potential pharmacological effects, this compound has attracted significant interest in the fields of medicinal chemistry and organic synthesis.

Check Digit Verification of cas no

The CAS Registry Mumber 1441769-24-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,4,1,7,6 and 9 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1441769-24:
(9*1)+(8*4)+(7*4)+(6*1)+(5*7)+(4*6)+(3*9)+(2*2)+(1*4)=169
169 % 10 = 9
So 1441769-24-9 is a valid CAS Registry Number.

1441769-24-9Upstream product

1441769-24-9Relevant articles and documents

NOVEL PYRAZOLO PYRIMIDINE DERIVATIVES AND THEIR USE AS MALT1 INHIBITORS

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Page/Page column 80; 81, (2015/12/31)

The present invention describes new pyrazolo-pyrimidine derivatives of formula (I) or a pharmaceutically acceptable salt thereof; (I) wherein, R1 is halogen, cyano, or C1-C3alkyl optionally substituted by halogen; R2 is C1-C6alkyl optionally substituted one or more times by C1-C6alkyl, C2-C6alkenyl, hydroxyl, N,N-di-C1-C6alkyl amino, N-mono-C1-C6alkyl amino, O-Rg, Rg, phenyl, or by C1-C6alkoxy wherein said alkoxy again may optionally be substituted by C1-C6alkoxy, N,N-di-C1-C6alkyl amino, Rg or phenyl; C3-C6cycloalkyl optionally substituted by C1-C6alkyl, N,N-di-C1-C6alkyl amino or C1-C6alkoxy-C1-C6alkyl, and/or two of said optional substituents together with the atoms to which they are bound may form an annulated or spirocyclic 4 - 6 membered saturated heterocyclic ring comprising 1 - 2 O atoms; phenyl optionally substituted by C1-C6alkoxy; a 5 - 6 membered heteroaryl ring having 1 to 3 heteroatoms selected from N and O said ring being optionally substituted by C1-C6alkyl which may be optionally substituted by amino or hydroxy; Rg; or N,N-di-C1-C6alkyl amino carbonyl; and R is phenyl independently substituted two or more times by Ra, 2-pyridyl independently substituted one or more times by Rb, 3-pyridyl independently substituted one or more times by Rc, or 4-pyridyl independently substituted one or more times by Rd; which are generally interacting with MALT1 proteolytic and/or autoproteolytic activity, and in particular which may inhibit said activity. The present invention further describes the synthesis of said new pyrazolo-pyrimidine derivatives, their use as a medicament, especially by interacting with MALT1 proteolytic and/or autoproteolytic activity.

PYRAZOLO[3,4-D]PYRIMIDINONE COMPOUNDS AS INHIBITORS OF THE P53/MDM2 INTERACTION

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Page/Page column 85, (2014/08/07)

The invention relates to compounds of formula (I): as described herein, pharmaceutical preparations comprising such compounds, uses and methods of use for such compounds in the treatment of a disorder or a disease mediated by the activity of MDM2 and/or MDM4, and combinations comprising such compounds.

IMIDAZOPYRROLIDINONE COMPOUNDS

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, (2013/08/15)

The invention relates to compounds of formula (I): (I) as described herein, pharmaceutical preparations comprising such compounds, uses and methods of use for such compounds in the treatment of a disorder or a disease mediated by the activity of MDM2 and/or MDM4, and combinations comprising such compounds.

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