144187-44-0

Basic information

• Product Name: AKOS B022015
• Synonyms: ART-CHEM-BB B022015;AKOS B022015;TIMTEC-BB SBB009591;5-Fluoro-2-morpholin-4-yl-phenylamine
• CAS NO: 144187-44-0
• Molecular Formula: C₁₀H₁₃FN₂O
• Molecular Weight: 196.22
• Mol File: 144187-44-0.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: AKOS B022015(CAS DataBase Reference)
• NIST Chemistry Reference: AKOS B022015(144187-44-0)
• EPA Substance Registry System: AKOS B022015(144187-44-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 144187-44-0(Hazardous Substances Data)

Upstream product

• 446-09-3 2-bromo-5-fluoronitrobenzene 
• 238418-75-2 4-(4-fluoro-2-nitro-phenyl)morpholine 

Downstream Products

• 1253380-02-7 1-[(2-chloro-4-fluorophenyl)methyl]-4-[5-fluoro-2-(4-morpholinyl)phenyl]-2,3-piperazinedione 
• 131676-85-2 N-(5-fluoro-2-morpholinophenyl)isobutyramidine 
• 131679-55-5 5-fluoro-2-morpholinophenyl isothiocyanate 

Relevant articles and documents

Carbazole and Carboline Compounds for Use in the Diagnosis, Treatment, Alleviation or Prevention of Disorders Associated with Amyloid or Amyloid-Like Proteins

The present invention relates to novel compounds that can be employed in the diagnosis, treatment, alleviation or prevention of a group of disorders and abnormalities associated with amyloid proteins and amyloid-like proteins, such as Alzheimer's disease. Precursors for the preparation of the compounds according to the present invention are also provided.

ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES

The invention provides compounds having activity as bacterial RNA polymerase inhibitors and antibacterial agents, as well as compositions comprising the compounds and methods for their use. Specifically, phenylalanineamide and tyrosinamide compounds are disclosed that have inhibitory activity toward mycobacterium tuberculosis RNA polymerase. Use of these compounds in the treatment o prevention of M. tuberculosis infections in a mammal, is disclosed.

QUINOLONE COMPOUND AND PHARMACEUTICAL COMPOSITION

The present invention provides a quinolone compound represented by General Formula (1) or a salt thereof, wherein R1 represents a hydrogen atom, etc.; R2 represents a hydrogen atom, etc.; R3 represents a phenyl group optio