144239-98-5

Upstream product

• 1826-67-1 vinyl magnesium bromide 
• 87694-53-9 Boc-Phe-OH N,O-dimethyl hydroxamate 
• 72155-45-4 Boc-L-phenylalaninal 
• 66605-57-0 (S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol 
• 137278-22-9 ((S)-1-Benzyl-2-oxo-but-3-enyl)-carbamic acid tert-butyl ester 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 51987-73-6 (S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester 

Downstream Products

• 144164-48-7 Methanesulfonic acid 1-((S)-1-tert-butoxycarbonylamino-2-phenyl-ethyl)-allyl ester 
• 114671-12-4 (4S,5S)-5-ethenyl-4-phenylmethyloxazolidin-2-one 
• 124915-64-6 (4S,5R)-5-ethenyl-4-phenylmethyloxazolidin-2-one 
• 265996-19-8 (4S,5RS)-5-ethenyl-4-phenylmethyloxazolidin-2-one 
• 1329428-04-7 (2S,3S)-tert-butyl 1-phenyl-3-(phenylthio)pent-4-en-2-ylcarbamate 
• 1329428-03-6 (2S,3S)-tert-butyl 1-phenyl-3-(thiophen-2-ylthio)pent-4-en-2-ylcarbamate 
• 1329428-02-5 (2S,3S)-tert-butyl 3-(methylthio)-1-phenylpent-4-en-2-ylcarbamate 
• 1329427-83-9 (2S,3S)-3-[(1,3-dioxoisoindolin-2-yl)sulfanyl]-1-phenylpent-4-en-2-yl carbamic acid tert-butyl ester 
• 1140504-27-3 tert-butyl (S,E)-1-benzyl-4-trimethylsilanyl-but-2-enyl-carbamate 
• 134804-71-0 (2S,3S,4S)-2-amino-4-<<(tert-butyloxy)carbonyl>amino>-1,5-diphenyl-3-hydroxypentane 
• 134804-71-0 (2R,3R,4S)-2-amino-4-<<(tert-butyloxy)carbonyl>amino>-1,5-diphenyl-3-hydroxypentane 
• 143838-04-4 (3-Azido-1-benzyl-2-hydroxy-4-phenyl-butyl)-carbamic acid tert-butyl ester 
• 134806-56-7 [(S)-1-(3-Benzyl-oxiranyl)-2-phenyl-ethyl]-carbamic acid tert-butyl ester 
• 854102-47-9 cis-(2S)-2-<<(tert-butyloxy)carbonyl>amino>-1,5-diphenylpent-3-ene 

Relevant academic research and scientific papers

Synthesis and biological evaluations of novel endomorphin analogues containing α-hydroxy-β-phenylalanine (AHPBA) displaying mixed μ/δ opioid receptor agonist and δ opioid receptor antagonist activities

A novel series of endomorphin-1 (EM-1) and endomorphin-2 (EM-2) analogues was synthesized, incorporating chiral α-hydroxy-β-phenylalanine (AHPBA), and/or Dmt1-Tic2 at different positions. Pharmacological activity and metabolic stabil

Allosteric regulation of the conformational dynamics of a cavitand receptor

Inspired by allostery in nature, we synthesized cavitand 1 and investigated regulation of its conformational dynamics. Quantitative 1H NMR studies have revealed that the rate of the conformational isomerization of 1 can be modulated using the e

Enantiospecific formation of 3,6-dihydro-1H-pyridin-2-ones: Low-pressure palladium-catalysed decarboxylative carbonylation of 3-tosyl-5-vinyloxazolidin- 2-ones

Palladium-catalysed decarboxylative carbonylation of 3-tosyl-5- vinyloxazolidin-2-ones 5 occurs at atmospheric pressure to give 1-tosyl-3,6-dihydro-1H-pyridin-2-ones 6. The reaction proceeds with no loss of enantiopurity and detosylation with sodium napht

Inactivation of serine protease, α-chymotrypsin by fluorinated phenylalanine analogues

Fluorinated phenylalanine analogues were found to be slow-binding or reversible competitive inhibitors of α-chymotrypsin. A series of these compounds were designed to inactivate α-chymotrypsin as a result of the formation of hydrogen-bonding between fluorine atom of the inhibitors and the amide protons known as oxy-anion hole in the active-site of serine and cysteine proteases.