1442431-84-6

Basic information

• Product Name: ethyl 5-(2-(tert-butyl)-6-(neopentylamino)pyridin-4-yl)-1-(cyclohexylmethyl)-2-methyl-1H-pyrrole-3-carboxylate
• Synonyms: ethyl 5-(2-(tert-butyl)-6-(neopentylamino)pyridin-4-yl)-1-(cyclohexylmethyl)-2-methyl-1H-pyrrole-3-carboxylate
• CAS NO: 1442431-84-6
• Molecular Weight: 467.695
• Mol File: 1442431-84-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 5-(2-(tert-butyl)-6-(neopentylamino)pyridin-4-yl)-1-(cyclohexylmethyl)-2-methyl-1H-pyrrole-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 5-(2-(tert-butyl)-6-(neopentylamino)pyridin-4-yl)-1-(cyclohexylmethyl)-2-methyl-1H-pyrrole-3-carboxylate(1442431-84-6)
• EPA Substance Registry System: ethyl 5-(2-(tert-butyl)-6-(neopentylamino)pyridin-4-yl)-1-(cyclohexylmethyl)-2-methyl-1H-pyrrole-3-carboxylate(1442431-84-6)

Safety Data

• Hazardous Substances Data: 1442431-84-6(Hazardous Substances Data)

Upstream product

• 5813-64-9 2.2-dimethylpropylamine 
• 1442431-83-5 ethyl 5-(2-(tert-butyl)-6-(((trifluoromethyl)sulfonyl)oxy)pyridin-4-yl)-1-(cyclohexylmethyl)-2-methyl-1H-pyrrole-3-carboxylate 
• 857428-73-0 6-tert-butyl-4-hydroxy-1,2-dihydropyridin-2-one 
• 1442431-79-9 2-(benzyloxy)-4-bromo-6-(tert-butyl)pyridine 
• 1442431-80-2 2-(benzyloxy)-6-(tert-butyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 
• 1402890-08-7 4-bromo-6-tert-butylpyridin-2(1H)-one 
• 1442431-81-3 ethyl 5-(2-(benzyloxy)-6-(tert-butyl)pyridin-4-yl)-1-(cyclohexylmethyl)-2-methyl-1H-pyrrole-3-carboxylate 
• 1442431-82-4 ethyl 5-(2-(tert-butyl)-6-hydroxypyridin-4-yl)-1-(cyclohexylmethyl)-2-methyl-1H-pyrrole-3-carboxylate 

Downstream Products

• 1442431-85-7 5-(2-(tert-butyl)-6-(neopentylamino)pyridin-4-yl)-1-(cyclohexylmethyl)-2-methyl-1H-pyrrole-3-carboxylic acid 

Relevant articles and documents

PYRROLO CARBOXAMIDES AS MODULATORS OF ORPHAN NUCLEAR RECEPTOR RAR-RELATED ORPHAN RECEPTOR-GAMMA (ROR?, NR1F3) ACTIVITY AND FOR THE TREATMENT OF CHRONIC INFLAMMATORY AND AUTOIMMUNE DISEASES

The invention provides modulators for the orphan nuclear receptor ROR? and methods for treating ROR? mediated diseases by administrating these novel ROR? modulators to a human or a mammal in need thereof. Specifically, the present invention provides pyrrolo carboxamide compounds of Formula (1) and the enantiomers, diastereomers, N-oxides, tautomers, solvates and pharmaceutically acceptable salts thereof.