1442981-61-4

Basic information

• Product Name: C₁₈H₂₇NO₂
• Synonyms: C₁₈H₂₇NO₂
• CAS NO: 1442981-61-4
• Molecular Weight: 289.418
• Mol File: 1442981-61-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₂₇NO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₂₇NO₂(1442981-61-4)
• EPA Substance Registry System: C₁₈H₂₇NO₂(1442981-61-4)

Safety Data

• Hazardous Substances Data: 1442981-61-4(Hazardous Substances Data)

Upstream product

• 109838-88-2 1-benzyl-4-fluoropiperidine 

Relevant articles and documents

Fe-catalysed Kumada-type alkyl-alkyl cross-coupling. Evidence for the intermediacy of Fe(i) complexes

A novel Fe-NHC catalytic system allows the alkyl-alkyl cross-coupling reaction of alkyl halides and alkylmagnesium reagents has been developed. To our knowledge, this is the first Fe-catalysed Kumada-type coupling for the formation of C(sp3)-C(sp3) bonds in the presence of functional groups. The process takes place under mild conditions, avoiding the formation of β-elimination products. Mechanistic studies suggest the intermediacy of Fe(i) complexes, formed by reduction with the Grignard reagent, as the active species.