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Tetrazolo[5,1-a]isoquinoline is a heterocyclic compound characterized by the fusion of a tetrazole ring (a five-membered ring with four nitrogen atoms) to an isoquinoline ring system (a tricyclic aromatic compound derived from quinoline). This unique structure endows the molecule with a range of potential applications in medicinal chemistry, particularly as a scaffold for the development of new drugs. The compound's properties, such as its stability and reactivity, make it an interesting target for synthetic chemists. Tetrazolo[5,1-a]isoquinolines have been explored for their potential as anticancer agents, among other therapeutic uses, due to their ability to form stable complexes with metal ions and their potential to interact with biological targets.

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  • 1443-60-3 Structure
  • Basic information

    1. Product Name: Tetrazolo[5,1-a]isoquinoline
    2. Synonyms:
    3. CAS NO:1443-60-3
    4. Molecular Formula: C9H6N4
    5. Molecular Weight: 170.173
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1443-60-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Tetrazolo[5,1-a]isoquinoline(CAS DataBase Reference)
    10. NIST Chemistry Reference: Tetrazolo[5,1-a]isoquinoline(1443-60-3)
    11. EPA Substance Registry System: Tetrazolo[5,1-a]isoquinoline(1443-60-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1443-60-3(Hazardous Substances Data)

1443-60-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1443-60-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,4 and 3 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1443-60:
(6*1)+(5*4)+(4*4)+(3*3)+(2*6)+(1*0)=63
63 % 10 = 3
So 1443-60-3 is a valid CAS Registry Number.

1443-60-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name tetrazolo[5,1-a]isoquinoline

1.2 Other means of identification

Product number -
Other names Tetrazolo[5,1-a]isochinolin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1443-60-3 SDS

1443-60-3Relevant articles and documents

Reaction of N-fluoropyridinium fluoride with isonitriles and TMSN 3: A convenient one-pot synthesis of tetrazol-5-yl pyridines

Kiselyov, Alexander S.

, p. 4851 - 4854 (2007/10/03)

Reaction of N-fluoropyridinium fluoride generated in situ with a series of isonitriles and TMSN3 led to the formation of the corresponding tetrazol-5-yl pyridines in good yields (37-84%). A similar reaction sequence for quinoline yielded the respective derivatives of 2-quinoline. The proposed reaction mechanism involves the intermediate formation of a highly reactive carbene species.

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