1443017-99-9Relevant academic research and scientific papers
Palladium-catalyzed direct C-H arylation of cyclic enaminones with aryl iodides
Yu, Yi-Yun,Bi, Lei,Georg, Gunda I.
, p. 6163 - 6169 (2013/07/26)
A ligand-free method for the Pd-catalyzed direct arylation of cyclic enaminones using aryl iodides was developed. This method can be applied to a wide range of cyclic enaminones and aryl iodides with excellent C5-regioselectivity. Using widely available aryl iodides, the generality of this transformation provides easy access to a variety of 3-arylpiperidine structural motifs.
