144302-72-7Relevant academic research and scientific papers
Iron carbonyl promoted conversion of α,ω-diynes to (cyclopentadienone)iron complexes
Pearson, Anthony J.,Shively Jr., Raymond J.,Dubbert, Robert A.
, p. 4096 - 4104 (2008/10/08)
An efficient high-yielding procedure is described for the intramolecular carbonylative coupling of α,ω-diynes to give cyclopentadienone-Fe(CO)3 complexes. Exchanging one CO ligand with PPh3 affords control over the manipulation of α,α′-trimethylsilyl-substituted cyclopentadienone complexes. The preparation of α,ω-diynes with a hydroxy group adjacent to one alkyne unit leads to modest stereocontrol upon cyclization forming the Fe(CO)3 complex. The hydroxy-substituted complex was oxidized to ketone. Borohydride reduction and Grignard addition to the ketone proceed anti to the Fe(CO)3 moiety. The X-ray crystal structure of C40H31FeO3P shows that it crystallizes in the monoclinic space group P21/n in a unit cell of dimensions a = 12.0595 (24), b = 13.3926 (30), c = 19.0682 (38) A?, β = 93.98 (2)°, with Z = 4.
