1443055-92-2

Basic information

• Product Name: 1,3-bis(4-(trifluoromethyl)phenyl)butan-1-one
• CAS NO: 1443055-92-2
• Molecular Weight: 360.299
• Mol File: 1443055-92-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,3-bis(4-(trifluoromethyl)phenyl)butan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-bis(4-(trifluoromethyl)phenyl)butan-1-one(1443055-92-2)
• EPA Substance Registry System: 1,3-bis(4-(trifluoromethyl)phenyl)butan-1-one(1443055-92-2)

Safety Data

• Hazardous Substances Data: 1443055-92-2(Hazardous Substances Data)

Upstream product

• 1737-26-4 1-(4-trifluorophenyl)ethanol 

Relevant articles and documents

Ruthenium-catalyzed self-coupling of primary and secondary alcohols with the liberation of dihydrogen

The dehydrogenative self-condensation of primary and secondary alcohols has been studied in the presence of RuCl2(IiPr)(p-cymene). The conversion of primary alcohols into esters has been further optimized by using magnesium nitride as an additive, which allows the reaction to take place at a temperature and catalyst loading lower than those described previously. Secondary alcohols were dimerized into racemic ketones by a dehydrogenative Guerbet reaction with potassium hydroxide as the additive. The transformation gave good yields of the ketone dimers with a range of alkan-2-ols, whereas more substituted secondary alcohols were unreactive. The reaction proceeds by dehydrogenation to the ketone, followed by an aldol reaction and hydrogenation of the resulting enone.