1443118-41-9

Basic information

• Product Name: C₃₁H₂₆⁽²⁾H₁₄N₂O₁₀S
• Synonyms: C₃₁H₂₆⁽²⁾H₁₄N₂O₁₀S
• CAS NO: 1443118-41-9
• Molecular Weight: 646.621
• Mol File: 1443118-41-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₁H₂₆⁽²⁾H₁₄N₂O₁₀S(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₁H₂₆⁽²⁾H₁₄N₂O₁₀S(1443118-41-9)
• EPA Substance Registry System: C₃₁H₂₆⁽²⁾H₁₄N₂O₁₀S(1443118-41-9)

Safety Data

• Hazardous Substances Data: 1443118-41-9(Hazardous Substances Data)

Upstream product

• 1263999-48-9 (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol-d2 
• 120-80-9 benzene-1,2-diol 
• 127132-32-5 ethyl N-{[(1,1-dimethylethyl)oxy]carbonyl}-O-(phenylmethyl)-L-tyrosinate 
• 1443118-39-5 C₃₈H₃₂⁽²⁾H₁₄N₂O₁₀S 
• 1443118-37-3 C₃₅H₂₈⁽²⁾H₁₄N₂O₁₀S 
• 1263999-52-5 (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl-d2 4-nitrophenylcarbonate 
• 1263999-44-5 (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl acetate-d2 
• 1443118-33-9 C₈H₁₀⁽²⁾H₂O₄ 
• 1443118-32-8 C₆H₇⁽²⁾HO₃ 
• 1443118-31-7 C₇H₉⁽²⁾HO₂ 
• 1256492-90-6 C₇H₈⁽²⁾HBrO₂ 
• 1443118-24-8 C₂₈H₂₂⁽²⁾H₁₂N₂O₆S 
• 1256492-92-8 C₃₃H₃₀⁽²⁾H₁₂N₂O₈S 
• 1256492-68-8 C₇H₃⁽²⁾H₂ClO₄S 

Relevant articles and documents

Synthesis and pharmacokinetic profile of highly deuterated brecanavir analogs

Several highly deuterated analogs of the HIV-1 protease inhibitor brecanavir have been prepared to study the effect of deuterium upon metabolic stability. The sites for deuterium incorporation were initially chosen to maximize the potential for a kinetic isotope effect; locations where C-H bond breaking is the rate limiting step. The analogs have been profiled in both in vitro and in vivo pharmacokinetic studies and the result will be described herein.