144316-86-9 Usage
Description
6'-carboxyl-2',7'-dichlorodihydrofluorescein is a chemical compound that belongs to the class of organic compounds known as fluoresceins. It is a synthetic dye with pH-sensitive properties, capable of undergoing color changes depending on the pH level. 6'-carboxyl-2',7'-dichlorodihydrofluorescein has the unique ability to convert from a colorless non-fluorescent state to a green fluorescent state in the presence of reactive oxygen species, making it a potential pH sensitivity agent and a useful tool in medical research for detecting and measuring oxidative stress in cells.
Uses
Used in Medical Research:
6'-carboxyl-2',7'-dichlorodihydrofluorescein is used as a pH sensitivity agent for probing membrane-permeant weak acid and weak base conjugate systems. Its ability to change color and fluorescence in response to pH variations makes it a valuable tool in studying cellular processes and monitoring pH changes within cells.
Used in Oxidative Stress Detection:
6'-carboxyl-2',7'-dichlorodihydrofluorescein is used as a fluorescent indicator for detecting and measuring the levels of oxidative stress in cells. Its conversion from a colorless non-fluorescent compound to a green fluorescent one in the presence of reactive oxygen species allows researchers to monitor and quantify oxidative stress, which is crucial in understanding the role of reactive oxygen species in various diseases and conditions.
Used in Drug Delivery Systems:
Although not explicitly mentioned in the provided materials, 6'-carboxyl-2',7'-dichlorodihydrofluorescein could potentially be used in drug delivery systems as a pH-sensitive component. Its ability to change fluorescence properties in response to pH variations could be harnessed to develop targeted drug delivery systems that release their payload in response to specific pH environments, such as the acidic conditions found in tumor tissues or inflamed regions.
Check Digit Verification of cas no
The CAS Registry Mumber 144316-86-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,3,1 and 6 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 144316-86:
(8*1)+(7*4)+(6*4)+(5*3)+(4*1)+(3*6)+(2*8)+(1*6)=119
119 % 10 = 9
So 144316-86-9 is a valid CAS Registry Number.
