1443208-04-5

Basic information

• Product Name: N-(3-phenylpropyl)-3-(piperidin-4-yloxy)benzo[b]thiophene-2-carboxamide
• CAS NO: 1443208-04-5
• Molecular Weight: 394.538
• Mol File: 1443208-04-5.mol

Chemical Properties

• CAS DataBase Reference: N-(3-phenylpropyl)-3-(piperidin-4-yloxy)benzo[b]thiophene-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-phenylpropyl)-3-(piperidin-4-yloxy)benzo[b]thiophene-2-carboxamide(1443208-04-5)
• EPA Substance Registry System: N-(3-phenylpropyl)-3-(piperidin-4-yloxy)benzo[b]thiophene-2-carboxamide(1443208-04-5)

Safety Data

• Hazardous Substances Data: 1443208-04-5(Hazardous Substances Data)

Upstream product

• 2038-57-5 3-Phenylpropan-1-amine 
• 1416051-63-2 3-((1-(tert-butoxycarbonyl)piperidin-4-yl)oxy)benzo[b]thiophene-2-carboxylic acid 

Relevant articles and documents

Design and synthesis of high affinity inhibitors of Plasmodium falciparum and Plasmodium vivax N-myristoyltransferases directed by ligand efficiency dependent lipophilicity (LELP)

N-Myristoyltransferase (NMT) is an essential eukaryotic enzyme and an attractive drug target in parasitic infections such as malaria. We have previously reported that 2-(3-(piperidin-4-yloxy)benzo[b]thiophen-2-yl)-5-((1,3, 5-trimethyl-1H-pyrazol-4-yl)meth

NOVEL COMPOUNDS AND THEIR USE IN THERAPY

The invention provides compounds which inhibit N-myristoyltransferase and are selective for protozoal N-myristoyltransferase and, consequently suitable to treat microbial infections, including viral and fungal infections, and protozoan infections such as malaria, leishmaniasis and sleeping sickness.