1443219-25-7Relevant academic research and scientific papers
Potent naphthoquinones against antimony-sensitive and -resistant Leishmania parasites: Synthesis of novel α- And nor-α-lapachone-based 1,2,3-triazoles by copper-catalyzed azide-alkyne cycloaddition
Guimar?es, Tiago T.,Pinto, Maria Do Carmo F.R.,Lanza, Juliane S.,Melo, Maria N.,Do Monte-Neto, Rubens L.,De Melo, Isadora M.M.,Diogo, Emilay B.T.,Ferreira, Vitor F.,Camara, Celso A.,Valen?a, Wagner O.,De Oliveira, Ronaldo N.,Frézard, Frédéric,Da Silva Júnior, Eufranio N.
, p. 523 - 530 (2013)
Continuing our screening program for novel anti-parasite compounds, we synthesized seven 1,4-naphthoquinones coupled to 1,2,3-triazoles, five nor-β-lapachone-based 1,2,3-triazoles and ten α-lapachone-based 1,2,3-triazoles. These and other naphthoquinonoid
Synthesis and anti-Trypanosoma cruzi activity of naphthoquinone-containing triazoles: Electrochemical studies on the effects of the quinoidal moiety
Diogo, Emilay B.T.,Dias, Gleiston G.,Rodrigues, Bernardo L.,Guimaraes, Tiago T.,Valenca, Wagner O.,Camara, Celso A.,De Oliveira, Ronaldo N.,Da Silva, Mauro G.,Ferreira, Vitor F.,De Paiva, Yen Galdino,Goulart, Marilia O.F.,Menna-Barreto, Rubem F.S.,De Castro, Solange L.,Da Silva Junior, Eufranio N.
, p. 6337 - 6348 (2013/10/22)
In our continued search for novel trypanocidal compounds, twenty-six derivatives of para- and ortho-naphthoquinones coupled to 1,2,3-triazoles were synthesized. These compounds were evaluated against the infective bloodstream form of Trypanosoma cruzi, th
