1443299-02-2Relevant academic research and scientific papers
Pd-catalyzed regioselective allylation of Mono- and disubstituted hydrazines
Tsupova, Svetlana,Maeeorg, Uno
supporting information, p. 3381 - 3383 (2013/07/26)
Palladium-catalyzed allylation of hydrazines using allyl alcohols is reported. This highly efficient protocol furnishes monoallylated hydrazines selectively, in 27-99% yields. Following an optimization of the reaction conditions and of the Pd-ligands, the allylations of both mono- and disubstituted hydrazines were investigated, as well as the effects of C2-substitution on the allylating agent. Of particular interest, a novel method for the selective monoallylation of monosubstituted hydrazines is demonstrated.
