1443380-67-3Relevant academic research and scientific papers
Direct sp3 C-H amination of nitrogen-containing benzoheterocycles mediated by visible-light-photoredox catalysts
Miyake, Yoshihiro,Nakajima, Kazunari,Nishibayashi, Yoshiaki
supporting information, p. 16473 - 16477 (2013/02/22)
Visible-light-mediated direct sp3 C-H amination of benzocyclic amines via α-aminoalkyl radicals by using photoredox catalysts is described here. The obtained N,N-acetals were also successfully applied for carbon-carbon bond forming reactions with carbon nucleophiles. The procedure is suitable for a late-stage modification of C-H bonds to C-C bonds. Amination sees the light: Visible-light-mediated direct sp3 C-H amination of benzocyclic amines via α-aminoalkyl radicals by using photoredox catalysts is described here (see scheme). The obtained N,N-acetals were also successfully applied for carbon-carbon bond-forming reactions with carbon nucleophiles. The procedure is suitable for a late-stage modification of C-H bonds to C-C bonds.
